Menthol has roots in traditional medicine well before the global pharmaceutical industry ever codified its standards. People across Asia, especially in China and India, learned from generations past that oils distilled from mint leaves delivered cooling sensations and relief for minor ailments. By the late 1700s, Japanese chemists achieved crystallization, making it easier to use and transport. The pharmaceutical industry took notice in the 19th century as demand for consistent and reliable ingredients grew. Organizations like the British Pharmacopoeia (BP), European Pharmacopoeia (EP), and United States Pharmacopeia (USP) eventually formalized standards for menthol, anchoring everything from the method of isolation to acceptable impurity levels. Judging by the hundreds of tons produced yearly, today’s pharma-grade menthol stands on two centuries of technical refinement and regulatory discipline.
Menthol for pharmaceutical use often comes as colorless or white crystals packed in well-sealed containers. The smell carries that unmistakable peppermint character, sharp and clean, sometimes almost overwhelming when a fresh package opens. This compound may look like an old-fashioned home remedy, but it meets strict batch-testing requirements. Manufacturers must demonstrate lot-to-lot consistency, batch records, and careful traceability through every step. Menthol’s main source remains Mentha arvensis and Mentha piperita, and synthetic processes have scaled up in recent years to meet big demand while helping keep natural mint crops from becoming overharvested. Each drum or pouch will have labeling that features not just the name and strength but also batch number, expiry date, and storage guidance.
Good-quality menthol should deliver clear, sharp crystals, melting easily just above room temperature—around 42 to 45 °C. Press a crystal on your skin, and it cools instantly as it dissolves, thanks to activation of TRPM8 ion channels in the skin’s nerves. Water doesn’t dissolve menthol well, but alcohol and ether do, which gives chemists flexibility during formulation. The core chemical descriptor is C10H20O, a monoterpene alcohol. The industry focuses on l-menthol for its superior cooling effect; d-menthol and racemic mixtures occur sometimes but won’t deliver the same punch. Companies routinely use chromatography and polarimetry to check for purity and enantiomeric excess. High-end grades keep impurities—like other terpenes or isomenthol—well below 1%.
Regulators insist on a series of laboratory tests before menthol ever ends up in medicine. The BP, EP, and USP all demand a minimum purity of 99%. Moisture must stay below 0.3%. Limits on heavy metals, especially lead and arsenic, serve as safeguards, and one often spots certificates specifying less than 0.001% of each. Each batch’s container gets a detailed label—not just the name and grade, but warnings about storage temperature and needed ventilation. A full identification sheet runs with every shipment, helping trace any quality problem or recall down to a single pallet. Some countries call out voluntaries beyond international standards, such as “residue on ignition,” to prevent unintentional contamination with mineral remnants. This rigorous approach helps keep adulterated or low-purity stock out of finished drugs.
Most menthol on the market gets its start from mint oil, followed by fractional distillation and crystallization. Some operations have shifted to catalytic hydrogenation of thymol, a side-product of other essential oils, offering a more stable supply in years when mint harvests are poor or weather takes a toll. Whichever route, the key step is purification, using solvents at controlled temperatures to coax out crystal-clear menthol. Drying with inert gas cuts water content to match pharmacopeial demands. Scrupulous handling through glass or stainless-steel preserves flavor, aroma, and chemical stability—cheap metals just won’t work. Plant managers obsess over every stage, since a careless temperature spike or exposure to reactive metals can ruin a day or even a week’s run.
Menthol’s reactivity comes from its alcohol group, which reacts with acids to form esters, or can undergo oxidation to menthone, sometimes seen as an impurity. Drug developers sometimes modify menthol molecules to tweak their solubility or to join with other active ingredients. One example is menthyl esters, used to fine-tune absorption in topical applications. Polymer chemists sometimes attach menthol to backbone chains to improve the comfort of external medical patches. Menthol’s volatility keeps chemists careful: open beakers fill the lab with vapor quickly, demanding good ventilation and a light touch for precision work.
Menthol goes by many names, depending on the country and product line. Old pharmacopoeias call it “peppermint camphor,” while natural product catalogs list it as hexahydrothymol or m-racemic menthol. On most pharma paperwork, it shows up simply as l-menthol. Companies selling outside the Anglo sphere brand it under regional trade names. Some developers choose catchy product names for over-the-counter salves or drops, but legal requirements demand the chemical name stands out wherever regulated products are involved. This variety sometimes tricks less experienced buyers into thinking different sources give different molecules, but once checked, genuine BP, EP, or USP stock delivers the same crystals every time.
Clean facilities and worker safety go hand-in-hand whenever menthol is processed or packed in quantity. Skin and eye contact in high concentrations can burn or numb, so staff use gloves and safety glasses. Factory air moves fast to clear menthol vapor; anyone who’s ever stood too close to an open drum knows how strong those fumes get in seconds. Storage stays cool and away from strong acids or oxidizers. Food and pharma standards mean regular zone cleaning, zero tolerance for cross-contaminants, and paperwork for every container opened and resealed. Transport rules treat menthol as a flammable solid, so drivers need chemical hazard training and emergency spill plans. Modern factories run air sensors and have local exhaust systems posted over every mixing or weighing station.
Drug developers reach for menthol to punch up topical pain relief and congestion remedies. Its sharp, cooling kick shows up in cold and flu rubs, lozenges, and inhalants. Some mouthwashes and toothpastes use it—not just for flavor, but to help mask irritation or burning from active chemicals. Cough drops blend menthol to sooth throats and trick nerve endings while medicine does its longer work. Sports creams use it for that hit of comfort after a tough session. Oncology units even use menthol patches to cool oral mucositis. In certain regions, hospitals turn to it as a local anesthetic when more complex compounds run short. Chemists working on new delivery technologies use menthol’s volatility and solubility as a test point for slow-release patches and gels.
Academic and industry labs never really stop exploring new angles for menthol. My own work with emulsion technology opened up avenues where menthol acted as a solubility enhancer for poorly soluble drugs, giving higher bioavailability in test animals. Researchers keep uncovering how menthol interacts with cell membranes, impacting nerve responses to pain, itch, and heat. A recent trend looks at combining menthol with cannabinoids or non-steroidal compounds to reduce pain with fewer side effects. Dermatology specialists experiment with derivatives for more targeted cooling or longer-lasting effect without skin irritation. Formulation scientists love to tinker with emulsion and encapsulation strategies, aiming for timed release in creams or melts. These R&D investments, sometimes stretching years, end up rippling back to commercial pharmacies in new dosage forms and specialty blends.
Like so many natural extracts, menthol gets a mixed rap in toxicology debates. Decades of animal studies and case reports show menthol is generally safe at low doses, especially when kept diluted and not ingested in bulk. High exposures bring on nausea, dizziness, and—at very big doses—even convulsions, mostly among small children with direct ingestion. The trickiest part comes with multi-product use; unwary patients might get menthol in lozenges, vapor rubs, patches, and drinks, inching close to unsafe levels without realizing. Controlled studies in labs look for long-term effects; so far, the main risks cluster around very high local concentrations causing skin or mucous membrane damage. Guidelines in BP, EP, and USP restrict content in pediatric and sensitive products. Manufacturers face tight oversight from regulators who want to see exact toxicology cutoffs quoted on each new formulation.
The market for menthol in pharma continues to expand, almost hand in hand with growth in respiratory and topical medicine segments. Plant-based supply chains, once considered fragile, now get reinforced by synthetic routes, ensuring fewer shocks from poor mint seasons. Ongoing environmental research aims to drop solvent use and waste in menthol processing plants. Genetic work on mint crops may deliver more robust, pest-proof strains, lowering the environmental load from pesticides. The biggest opportunities aim beyond cooling itself: combining menthol with next-generation actives or tailoring its structure for nerve disorder treatments. Regulatory harmonization—drawing BP, EP, and USP standards even closer—could help streamline approvals and move good ideas from lab to shelf faster. My guess is the next decade will see more menthol-based innovations in pain management and respiratory products, with improved safety for young and elderly people built in from the start.
I have always seen a jar of menthol crystals tucked away in most home medicine cabinets. As a kid, menthol meant those cool, tingling ointments that soothed my chest during a cold. Years later, the same compound moved from a home remedy to an essential part of pharmaceutical labs. Menthol BP EP USP Pharma Grade doesn’t just promise a pleasant aroma; it stands for a commitment to safety and quality in medicine.
BP, EP, and USP each spell out a different set of standards—British Pharmacopoeia, European Pharmacopoeia, and United States Pharmacopeia. Menthol that says BP, EP, or USP on the label has been checked for purity, consistency, and safety. That means it has a strict certificate tied to it, reassuring both doctors and patients about what's inside the bottle. In my time discussing medicines with pharmacists, it’s clear that these standards aren’t just for show; they protect everyone from accidental impurities that could turn a helpful product into a dangerous one.
Low-grade menthol exists, but those products sometimes carry leftover chemicals, or their concentration drifts out of safe ranges. Pharmaceutical-grade menthol comes from either peppermint oil or is synthesized, then purified carefully. I’ve seen that high purity levels mean fewer allergic reactions and a lower risk of side effects. Only menthol that clears the bar set by BP, EP, or USP rules gets mixed into syrups, lozenges, rubs, and inhalers used by millions. This helps parents trust the cold medicines they buy for children.
Menthol’s cooling power soothes pain and irritation from sore throats, burns, and muscle aches. Walk into any pharmacy and you’ll see it in dozens of well-known brands. If someone has ever used a menthol ointment, nasal inhaler, or a cough lozenge, they have felt its numbing effect. It doesn’t just mask pain—it can also help unclog airways. That’s why any slip in purity or quality would mean headaches for families and front-line healthcare workers. Fake or low-grade menthol has caused recalls and pharmacy warnings in the past.
The process of producing BP EP USP grade menthol is tough. Every batch undergoes tests for purity, strength, and the absence of harmful residues. As someone who’s seen the inside of both medicine cabinets and laboratories, I know this sort of oversight is more than red tape. It protects the reputation of companies and, more importantly, the health of people who rely on predictable outcomes from their medications.
One problem that keeps surfacing is counterfeit or substandard menthol making its way into some global markets. Regulators, suppliers, and brands must work together: invest in traceable supply chains, roll out more rapid tests, and educate buyers about the risks of untested menthol. People making purchasing decisions—from procurement officers to parents—deserve clear information about where their menthol comes from and what makes certified grades trustworthy.
Menthol BP EP USP Pharma Grade carries real weight in healthcare. As consumers or industry insiders, we all shape the market by demanding transparency and quality. From my experience, a small step like reading a label or requesting a certificate can make sure the right menthol goes into trusted medicines and healthcare products.
Menthol probably holds a place in your home, though you might not think about it often. Open any jar of vapor rub, lozenge, or topical pain ointment—menthol takes center stage in each. Doctors and pharmacists often turn to menthol for its ability to create a cool sensation on the skin and inside the mouth. That cooling trick can mask pain or irritation, offering almost instant relief for sore throats, coughs, muscle aches, and minor burns. Cough drops count on menthol not just to soothe, but to break through stubborn congestion.
Years ago, I grabbed a menthol gel after a rough weekend of yard work. That familiar tingle set in almost right away, and the muscle pain faded into the background. Sports creams and patches rely on this same property. Menthol dulls the sensory nerves, making aches and strains feel less intense. In dental care, toothpastes and mouthwashes use menthol’s fresh taste to cover up bitterness and its gentle cooling to calm minor irritations.
People with eczema and dry skin often seek some measure of comfort from menthol creams. The chill distracts from itching and brings short-lived peace to skin that never seems to rest. Shampoos for dandruff and certain scalp conditions use menthol for this calming effect, lending a sense of relief that many find addictive.
Pharma-grade menthol comes with certifications—BP, EP, and USP—that matter to doctors, regulators, and patients. These grades mean the menthol’s purity is high enough for use in both traditional and Western medicine. Plenty of people in India and parts of Southeast Asia grew up with menthol balms as daily household staples for coughs, fevers, and headaches. Healers pair menthol with essential oils in herbal ointments, leaning on the natural cooling effect passed down through generations.
Pharmaceutical grade sounds technical but its impact reaches far past the hospital or pharmacy. Minty chewing gum, cooling candies, and flavored toothpicks all rely on menthol to brighten taste and freshness. Beverage makers put tiny amounts of menthol in some drinks to leave that crisp aftertaste consumers crave. Beyond flavor, menthol finds its way into toothpaste, mouthwash, and even aftershave—trusted for its clean, fresh feel.
Impurities can cause reactions, so top-grade menthol assures doctors and patients of safety. Pharma-grade menthol stands out because it meets strict standards—British Pharmacopoeia (BP), European Pharmacopoeia (EP), and United States Pharmacopeia (USP). Without these standards, fake or contaminated products could damage trust in what otherwise feels like a simple fix for pain or discomfort.
Plenty of people—myself included—prefer using trusted, well-tested products over mystery balms or unlabelled concoctions. The comfort in knowing what’s in a product and the backing from regulatory standards guides millions to choose menthol-based solutions. Clear labeling and quality controls steer people away from counterfeit goods, which can harm rather than help.
Pharma-grade menthol’s legacy keeps growing as researchers study its effects on nerve pathways and pain relief. Some scientists see chances for personalizing muscle rubs for older adults or developing low-irritation skincare for sensitive individuals. Investing in quality, education, and clear labeling could help more people get the relief they seek—safely and reliably.
Menthol pops up across a range of products, from medications that ease a sore throat to balms that cool a headache. Whether you pick up a peppermint-flavored toothpaste or cough drops at the pharmacy, menthol probably plays a part. Its sharp, cooling sensation isn’t just a matter of preference—it must also meet precise quality standards, especially if it's labeled as BP, EP, or USP grade.
The acronyms BP, EP, and USP point to different rulebooks for quality, purity, and safety. BP stands for the British Pharmacopoeia, EP means European Pharmacopoeia, and USP is United States Pharmacopeia. Each sets out what’s expected from pharmaceutical ingredients. The testing methods, limits on impurities, and acceptable physical properties aren’t always the same from one book to another.
Over years of working with pharmaceutical supply chains, I’ve seen the headaches that crop up when different companies use different grades. Say a maker of cough syrups in Europe orders menthol: they’re likely to seek EP-grade to sidestep regulatory pushback. A U.S. manufacturer preparing lozenges for the domestic market often prefers USP. A company exporting across continents might need all three certificates to keep things simple at customs and inspections.
I’ve also run into situations where two menthol batches look and smell the same but one batch can’t pass EP’s strict limit on isomenthone content, even if it does tick the boxes for USP. Pharmaceutical buyers care about those numbers because they point to both the safety and the effectiveness of the finished product.
The methods used to test menthol aren’t always aligned. EP, for example, tends to demand more exhaustive testing for related compounds, especially traces of other chemicals like neomenthol and menthone. BP sometimes sets its own purity standards, rooted in British regulatory preferences. USP may take a slightly different approach on allowable moisture levels or optical rotation—the way light bends as it passes through menthol crystals.
For a formulator making toothpaste or pain-relief ointment, those fine distinctions change sourcing and documentation. They also shape which batch of menthol can actually go into a new product rollout.
Global trade creates another layer of puzzle. I’ve met buyers nervous about a shipment of menthol from India labeled “USP grade” who need to check if it can pass muster for both U.S. and EU customers. There’s nothing arbitrary about those checks. Batches failing to meet the strictest requirement usually get rejected, delaying launches and increasing costs. In my experience, companies often aim for the highest bar that covers every possible market, even when it drives up purchase price.
One way forward involves building stronger bridges among testing laboratories worldwide. Sharing test data and making methods more transparent boost everyone’s confidence in the supply chain. Regulatory agencies slowly work toward harmonizing standards, but manufacturers must also invest in verifying every shipment—even if that means double testing or paying for broader certification.
For anyone managing a portfolio of menthol-based products, keeping up with these subtle but significant differences isn’t just paperwork; it’s about keeping shelves stocked without interruption and keeping consumer trust high.
Menthol grabs attention for its cooling sensation and fragrance, but its use in medicine invites stricter scrutiny. Pharmaceutical menthol labeled BP, EP, USP means it meets or exceeds pharmacopoeia benchmarks set by respected authorities in the UK, Europe, and the US. Those letters carry weight. They signal the menthol has passed purity, identity, and quality tests, usually involving minimum purity levels of 99%. Every batch faces checks for contaminants, such as heavy metals, pesticides, and residues. Factory records matter as much as laboratory tests. Reputable manufacturers don’t cut corners because regulators demand proof for every bit of menthol that enters a cough drop, nasal inhaler, or topical rub.
Menthol comes from several places: either extracted from peppermint oil or created synthetically. Both routes can land pharmaceutical grade material, as long as strict production practices seal the deal. Synthetic menthol, for instance, must avoid unwanted isomers or byproducts. The source isn’t the problem—lax manufacturing or poor controls open the door to impurities. Relying on certified suppliers helps reduce those risks.
Visit any pharmacy shelf and menthol pops up everywhere in medicated balms, sore throat sprays, and lozenges. Each of those products relies on detailed safety assessments. Centuries of safe use help menthol’s reputation. That doesn't mean blind trust, though. Regulatory scrutiny stays tight. The US FDA, European Medicines Agency, and similar agencies keep a close eye on allowed dosages and purity. Manufacturers send in data on each ingredient for product approvals. Adverse reactions—burning, allergies, or misuse—get tracked and can trigger recalls or rule changes. The system isn’t perfect, but safety concerns usually get addressed right away.
In my work with pharmaceutical ingredients, cutting corners on purity usually ends in trouble. Less pure menthol can introduce hazardous residues that defeat the point of using it in medicines. For example, some contaminants like camphor or certain solvents could harm sensitive patients. It’s not just about matching paperwork to a standard—labs use gas chromatography, infrared spectroscopy, and other tools to check each shipment. Anything below spec gets rejected. Pushing for quality might not earn headlines, but it sets the groundwork for trust in medicines.
Consumers sometimes worry—does “pharma grade” mean anything real, or is it just a label? The answer depends on the supply chain. Trustworthy pharma suppliers face inspections, surprise audits, and record-keeping checks. Regulatory agencies dig into the details. Problems start with unclear sourcing or companies that play fast and loose with documentation. Pharmacies, hospitals, and manufacturers know that one bad batch can ruin years of reputation. Consistent oversight and transparency give the public reasons to trust these grades, but there’s always room for improvement in traceability and reporting incidents.
Apart from strict standards, the safety of menthol also comes down to how it’s used. Packages require clear dosing instructions. Labels must highlight age limits and potential side effects, especially for young children or those with sensitive skin. Sometimes, pharmacists go the extra step, warning those with known allergies. Better public education could help customers use medicines wisely, especially in over-the-counter products where mistakes or overuse can cause harm. Pushing for better labeling and patient awareness goes hand in hand with chasing chemical purity.
Menthol BP EP USP pharma grade deserves its place in modern medicine, but that status should be backed by strict quality checks and full transparency. Relying on science, verified manufacturing, and clear communication stands as the safest path forward, for both patients and professionals.
Pharmaceutical menthol draws strict attention in the lab and warehouse for good reason. No one wants to risk active compounds losing their punch, and with menthol, it’s not only about keeping its potency—it’s about patient safety and reliable results. Knowing how to store menthol isn’t some distant concern for compliance managers. As someone who’s seen a product batch get written off from poor storage, I’ve learned the hard way: shortchanging on proper procedures ends up costing everyone.
Menthol feels safest in a cool, dry place, away from strong light and sources of heat. Left sitting near radiators or in direct sunlight, menthol can degrade and lose what makes it valuable to medicine makers. Temperatures between 15°C and 25°C tend to be the sweet spot—think of standard room temperature in a controlled facility, not a shipping container sitting out in the summer sun. Humidity creeps in more easily than you’d expect, especially in tropical areas. Even a small leak in packaging can encourage clumping, turning perfectly flowing crystals into one sticky lump that won’t discharge properly during mixing.
Many companies use stainless steel, high-density polyethylene, or glass containers for storage. These choices don’t just come from tradition; they’ve proven themselves reliable against corrosion and chemical reactions over time. It’s tempting to think plastic wrap or grocery bags could do the trick, but exposure to air can invite oxidation, which reduces menthol’s quality. I remember opening an aged drum once—what used to carry a crisp, sharp mint aroma smelled muddy and dull. That drum hadn’t been sealed tight.
Safety glasses, gloves, masks—these aren’t just meant for photos on the safety board. Menthol dust finds its way everywhere, and even short exposure stings the eyes and nasal passages. The fine powder floats easily, so opening large containers inside a fume hood or well-ventilated area makes life a lot easier. I’ve seen new lab staff get caught out by assuming menthol’s gentle smell lines up with its effect on skin and airways, only to regret it minutes later.
During weighing and transfer, spills can easily happen. Keeping the workspace uncluttered not only fits GMP checklists—it means less lost material and fewer slip hazards. Double-checking that scales and scooping tools stay dry prevents menthol from sticking and clumping, which otherwise slows down the whole workflow.
Distribution sometimes gets underestimated in risk assessments. Warehouses and couriers don’t always give menthol the respect it deserves. Shipments in thin plastic container liners or exposed to temperature swings sometimes end up rejected on arrival. Investing in insulated, sealed packaging and real-time monitoring for cargo holds up surprisingly well against typical shipping mix-ups. Clear, direct communication with transport partners helps avoid confusion about product sensitivity.
No one gets excited about temperature logs or double-sealed bins. Yet the attention given to storage and handling often determines whether menthol delivers its intended benefits or creates regulatory headaches. Money spent on the right tools—humidity sensors, tight-sealing containers, strict SOPs—pays off in fewer rejected lots and more trustworthy products reaching the patient. It's easy to underestimate the difference these details make until everything rides on a single lot’s reliability. Prioritizing careful, hands-on management at every step makes all the difference.
Names | |
Preferred IUPAC name | (1R,2S,5R)-2-isopropyl-5-methylcyclohexanol |
Other names |
Hexahydrothymol Mentha arvensis extract Levomenthol DL-Menthol Peppermint camphor |
Pronunciation | /ˈmɛn.θɒl/ biː piː iː piː juː ɛs piː ˈfɑː.mə ɡreɪd/ |
Identifiers | |
CAS Number | 2216-51-5 |
3D model (JSmol) | `3D model (JSmol)` string for **Menthol**: ``` C[C@H]1CC[C@H](C)CC1O ``` This is the **SMILES** string for Menthol (which is used by JSmol and other 3D molecular viewers). |
Beilstein Reference | 1719893 |
ChEBI | CHEBI:15478 |
ChEMBL | CHEMBL1388 |
ChemSpider | 7747 |
DrugBank | DB00825 |
ECHA InfoCard | echa.europa.eu/substance-information/-/substanceinfo/100.003.301 |
EC Number | 221-134-4 |
Gmelin Reference | Gmelin Reference: 1765 |
KEGG | C01045 |
MeSH | D046550 |
PubChem CID | 1254 |
RTECS number | **"OS7200000"** |
UNII | L7T10EIP3A |
UN number | Not regulated |
CompTox Dashboard (EPA) | DTXSID4036795 |
Properties | |
Chemical formula | C10H20O |
Molar mass | 156.27 g/mol |
Appearance | Colorless, transparent crystals or white crystalline powder with a characteristic odor |
Odor | Characteristic, peppermint-like |
Density | 0.89 g/cm³ |
Solubility in water | 1 g/L |
log P | 3.4 |
Vapor pressure | 0.055 mmHg at 25°C |
Acidity (pKa) | pKa = 16.0 |
Basicity (pKb) | 7.78 |
Refractive index (nD) | 1.46 |
Viscosity | 2.8 mPa.s (at 20°C) |
Dipole moment | 1.95 D |
Thermochemistry | |
Std molar entropy (S⦵298) | 216.6 J·mol⁻¹·K⁻¹ |
Std enthalpy of formation (ΔfH⦵298) | -377.0 kJ/mol |
Std enthalpy of combustion (ΔcH⦵298) | –3397 kJ/mol |
Pharmacology | |
ATC code | R05XA01 |
Hazards | |
Main hazards | Causes skin and eye irritation, harmful if swallowed, may cause respiratory irritation. |
GHS labelling | GHS02, GHS07 |
Pictograms | GHS07 |
Signal word | Warning |
Hazard statements | H315, H319, H335 |
Precautionary statements | Keep container tightly closed. Store in a cool, dry place. Avoid contact with eyes, skin, and clothing. Do not breathe dust or vapor. Wash thoroughly after handling. Use with adequate ventilation. |
NFPA 704 (fire diamond) | 1-1-0 |
Flash point | 94°C |
Autoignition temperature | 380°C |
Lethal dose or concentration | LD₅₀ (oral, rat): 3300 mg/kg |
LD50 (median dose) | MG/kg (mouse): 470 |
NIOSH | Not established |
PEL (Permissible) | PEL: "10 mg/m³ |
REL (Recommended) | 10 mg/kg body weight |
Related compounds | |
Related compounds |
Menthone Menthyl acetate Neomenthol Isomenthol Pulegone |