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Long before pharmaceutical industries filled the shelves with stabilized formulations and oral suspensions, castor oil carried a basic reputation—laxative, excipient, and even cosmetic ingredient. Turning raw castor oil into something far more specialized came out of necessity. The drive to mix oil and water more successfully led scientists to hydrogenate the fat portion, stabilizing the oil. Further modification came by grafting polyoxyethylene chains onto the backbone. This approach created an ingredient that didn’t just exist on a chemical registry; it actually helped solubilize hydrophobic drugs, keeping medications homogenous and effective for patients. Each major pharmacopoeia—British, European, US—eventually codified standards for this substance, recognizing the need for precisely defined quality. Over time, Polyoxyethylene 60 Hydrogenated Castor Oil (common trade names include Cremophor RH 60, HCO-60) didn’t just show up in the pharmaceutical world; it became essential for dozens of drug classes, from intravenous solutions to oral syrups, where older surfactants fell short.
Anyone who’s worked in a formulation lab knows the value of surfactants that actually work. Polyoxyethylene 60 Hydrogenated Castor Oil proves useful in dispersing oily active ingredients into water-based medicines, making it possible to deliver drugs that would otherwise cling hopelessly to glass or crystallize out. Industries favor it for its track record across regulatory agencies, including tight controls on composition and guaranteed consistency. Quality means more than just meeting a label claim; repeatable outcomes in drug delivery give patients steady results, batch after batch. In practice, the product comes as a thick, almost waxy paste or solid, slightly yellowish, with a mild fatty odor. It’s clearly labeled for every batch, with full documentation to back claims of USP, EP, or BP compliance.
Polyoxyethylene 60 Hydrogenated Castor Oil carries some predictable but valuable physical traits. At room temperature, the material sits solid or semi-solid—easy enough to handle yet soft enough to weigh. Melt it gently and you get a clear, tacky liquid, smooth for blending. It dissolves slowly in water, forming opalescent, stable colloidal solutions. Chemically, this surfactant is a non-ionic molecule—meaning it won’t mess with ionic drugs or destabilize delicate actives. The hydrogenated core offers high stability against oxidation, a key trait compared to non-hydrogenated oils which grow rancid over time. Polydispersity, hydrophilic-lipophilic balance (HLB around 15-16), average molecular weight, and acid value all show up in the technical specs—each number matching real-world observations in the lab, where little deviations have big impact on performance.
Pharma-grade Polyoxyethylene 60 Hydrogenated Castor Oil carries an extensive checklist of technical specifications. Viscosity, moisture content, acid value, saponification value, peroxide index—all get listed on the Certificate of Analysis for every lot shipped. Identity testing, via infrared spectroscopy or chromatographic assays, confirms the right material is in the drum. Regulatory compliance statements address questions for every major region: BP, EP, and USP monographs spell out purity requirements, absence of residual solvents, and thresholds for toxic byproducts like ethylene oxide. Safety labeling appears as well, noting both the pharmacopeial references and handling precautions—because even excipients, handled incorrectly, pose dangers. Multiple synonyms land in the documentation (Cremophor RH 60, HCO-60, PEG-60 Hydrogenated Castor Oil) bridging the gap between supplier catalogs and regulatory filing languages.
Turning raw castor oil into Polyoxyethylene 60 Hydrogenated Castor Oil requires several specific steps. Factories start by hydrogenating the oil, saturating the unsaturated bonds so the resulting fat resists oxidation and off-flavors. The hydrogenated oil, now more stable, then undergoes ethoxylation, reacting with ethylene oxide to grow long polyoxyethylene chains out from each hydroxyl group in the triglyceride. This part of the process controls the length and uniformity of the chains, targeting an average of 60 oxyethylene units per molecule. By keeping reaction conditions precise, and by stripping out unreacted ethylene oxide and related impurities under strong vacuum, operators end up with a substance consistently fitting pharmacopeial targets.
Mostly stable under typical pharmaceutical conditions, Polyoxyethylene 60 Hydrogenated Castor Oil still reacts the way any surfactant does—with strong acids or alkalis breaking it down, and high temperatures oxidizing the fatty core if carelessly stored. Ethoxylate chains can degrade in certain conditions, giving off aldehydes. Scientists have tried various tweaks over the years—adding antioxidants, shortening or lengthening the polyoxyethylene chains, or designing branched versions—each approach aiming for even better performance or lower toxicity. Some modifications focus on making the surfactant more biodegradable or altering its interaction with specific drug molecules, but the basic makeup remains highly effective for most pharmaceutical applications.
Walk through industry catalogs or check regulatory files, the same ingredient goes by several aliases. Polyoxyethylene 60 Hydrogenated Castor Oil appears as Cremophor RH 60 (BASF’s trademarked version), PEG-60 Hydrogenated Castor Oil, and HCO-60. Sometimes, pharma documentation uses the IUPAC name, but that barely ever shows up in supply chain discussions. Technical literature often cross-references these names, mostly to keep paperwork streamlined during global regulatory filings and cross-company development.
Pharmaceutical personnel treating Polyoxyethylene 60 Hydrogenated Castor Oil as just another oily compound risk missing critical safety details. Low acute toxicity at approved concentrations keeps it in oral, topical, and parenteral drugs, but it can trigger hypersensitivity responses in rare cases, notably in intravenous applications. I’ve seen reports of patients undergoing chemotherapy who struggle with reactions to the surfactant, not the drug itself. That situation set off a round of safety reviews, urging drug manufacturers to flag the excipient on product labels and train medical staff to monitor for allergic reactions. Manufacturing spaces handling this material must ensure proper ventilation and avoid skin contact. The material’s label always includes GHS pictograms, storage requirements (cool, dry, away from oxidizers), and incompatible materials—basic precautions that avoid mishaps over long-term storage or mixing. Audits by regulators frequently check for trace residual ethylene oxide, peroxides, and other impurities, holding factories to high standards for batch consistency and safety.
Beyond old laxative concoctions, Polyoxyethylene 60 Hydrogenated Castor Oil serves as a backbone excipient, especially when formulating poorly water-soluble active pharmaceutical ingredients. Its high HLB value pulls oily stuff into suspension—injectables like paclitaxel (where few alternatives succeed), oral emulsions, eye drops, and even topical creams with stubbornly insoluble actives. Look at fast-melt tablets or liquid-filled capsules, and this surfactant pops up in the paperwork, giving stable, patient-friendly forms that overcome solubility headaches. Nutraceuticals, veterinary medications, and some personal care products latch onto the pharma-grade version to reassure end-users and regulators the formulation won’t cross safety boundaries. The pharmaceutical industry counts on it as a near-default choice when oil and water must mix with long-term stability.
Active research continues around Polyoxyethylene 60 Hydrogenated Castor Oil. Scientists keep exploring ways to minimize hypersensitivity, increase bioavailability, and reduce formation of potentially reactive byproducts. Micellar technology developments turn this excipient into a carrier for peptides, poorly soluble small molecules, or even gene medicine payloads. Drug delivery teams focus on optimizing particle size, zeta potential, and performance consistency—knowing real-world success depends on matching lab advances with manufacturing realities. Industry consortia work on broadening the specification standards, with open data sharing to close technology gaps and preempt new regulatory demands. My experience in cross-functional pharmaceutical project teams always circles back to excipient innovation—not just for patenting a new process, but for practical gains in processability and product shelf life.
Toxicologists study Polyoxyethylene 60 Hydrogenated Castor Oil in search of both reassurance and warning signs. Animal testing shows low acute toxicity by oral, dermal, and IV routes, supporting regulatory claims of safety so long as formulation concentrations stay within prescribed boundaries. Investigators track both short-term inflammation and late manifestations—liver and kidney load especially. Some drug regimens that use high excipient loads need steady monitoring for these effects, reminding developers never to assume a surfactant can “disappear” just because it doesn’t show up in the therapeutic index. The excipient rarely provokes allergic or anaphylactoid reactions, but certain combinations, especially with cytotoxic agents, make clinicians watchful for adverse responses. Long-term safety studies, covering potential mutagenicity, carcinogenicity, and reproductive risks, have largely found no major red flags at pharma-grade purity. Still, clean manufacturing and rigorous impurity profiles remain mandatory—because safety in excipient sourcing supports the whole chain of drug trust, from factory to hospital bedside.
Looking ahead, Polyoxyethylene 60 Hydrogenated Castor Oil won’t fade out quietly. Pharma trends chase increasingly complex actives—peptides, RNA, poorly soluble new drugs—plus tighter calls for safer, purer excipients. Expect ongoing upgrades in raw material traceability, process analytics, and impurity detection. Biotech developers experiment with tweaks to the surfactant structure or combine it with synergistic excipients for ultra-stable injectable emulsions. There’s growing environmental interest as well: manufacturers develop greener process routes, possibly tapping renewable ethylene oxide sources and recyclable packaging. Regulatory scrutiny won’t ease up, so documentation, audit trails, and impurity thresholds will only get tighter. This excipient’s biggest advantage stems from decades of real-world track record, adaptability to new drug types, and proven compatibility with regulatory systems worldwide. The future, as always, depends on real results and the industry’s willingness to invest in better safety, greener chemistry, and data-driven development.
Polyoxyethylene 60 hydrogenated castor oil wears many hats in modern pharmaceuticals. This ingredient, born from castor oil and reworked through hydrogenation and mixing in polyethylene oxide, mixes the worlds of simple plant oils with chemistry. What emerges does work most oils can’t handle—it holds oil and water together, makes solutions clearer, and helps active medicine reach the right spot in the body. Drug makers grab it for things where easy swallowing, steady dosing, and predictable behavior count.
Oral liquid medicines often struggle when oil-based ingredients meet water. This compound acts as a bridge, so drugs like cough syrups or fat-soluble vitamins don’t separate in the bottle or leave a film in your mouth. Parents trying to give medicine to kids see the difference: fewer sticky residues and actual dosing as labeled. For solutions given in hospitals, such as injections, no one wants cloudiness or particles that clog an IV. This castor oil derivative keeps solutions clear and stable from factory to bedside.
Some life-saving medicines, especially those fighting infections or targeting cancer, ride with castor oil derivatives to get into the body. Certain antibiotics, like erythromycin or antifungals found in commercial markets, rely on this carrier to dissolve the medicine so it can enter the bloodstream. Doctors trust these mixtures to deliver steady, measured doses, with a low chance of reactions if used as advised.
It takes a lot to be considered “inert” or safe in medicine. Toxicology studies over decades have found that this compound, taken at intended amounts, doesn’t trigger worrisome effects. The U.S. Food and Drug Administration and European regulators greenlight it for a wide set of uses—not just in pills and syrups, but even creams or eye drops. Not all ingredients pass this test, which is why this compound stands out after so many years.
Not everything runs perfectly. A handful of people show allergic responses, or in rare situations, experience gastrointestinal distress with high doses. Hospitals adapted with careful dosing and labeling. Manufacturers changed quality testing, making sure to minimize harmful by-products. The value outweighs the risks, especially with continued regulation, better education for doctors, and honest communication with patients.
Demand for more stable, easy-to-use medicines grows. Newer biologics and protein therapies need specialized carriers, and researchers look at polyoxyethylene derivatives as building blocks. A push for transparency in pharmaceutical labeling helps, so patients and practitioners know what’s going into every dose. New technologies focus on reducing impurities, cutting reliance on animal or pollutant-rich sources, and tailoring these carriers for use in more fragile populations, including children and the elderly.
As someone with a chronic condition requiring liquid medicine, I’ve seen firsthand the value of clarity, stability, and pleasant taste. My pharmacist once explained how Important it is for a medicine to stay mixed and not spoil by the second week. A little piece of chemistry, like polyoxyethylene 60 hydrogenated castor oil, makes that possible and lowers the daily stress of illness. It’s not just an ingredient—it’s peace of mind for patients and families.
Polyoxyethylene 60 hydrogenated castor oil shows up on ingredient lists for all sorts of medicines: syrups, creams, injectables, and even vaccines. Most folks don’t notice it. It serves as an emulsifier, so oily and watery ingredients play nice together. Tough job in drugs, because a formula that separates doesn’t deliver the intended result. Scientists and doctors call it by its brand names—like Cremophor RH 60—but the backbone is still castor oil that’s been chemically tweaked.
I see this ingredient most often in cough syrups and some vitamin drops. Finished products end up clear and stable, without weird textures. The European Pharmacopeia and US Pharmacopeia both approve pharma-grade polyoxyethylene 60 hydrogenated castor oil for oral medicines. Studies show people generally tolerate it well, with only rare stomach discomfort or allergic reactions cropping up. For folks with castor oil allergies or very sensitive stomachs, though, a doctor’s guidance is smart. Regulatory authorities haven’t flagged major safety concerns. That matches up with my experience, where kids and adults alike use it in prescribed liquids, and side effects barely get mentioned.
This stuff pops up in ointments, gels, and skin creams. It helps keep the product smooth, and it stops oily ingredients from pooling at the top of a tube. For most skin types, topical use doesn’t raise red flags. Published research points out that irritation ranks low, unless applied to broken or irritated skin for prolonged periods. Cosmetic chemists I’ve talked to say it’s a reliable workhorse for getting even mixtures without causing rashes. If you’ve got a rare sensitivity or know you react badly to castor oil derivatives, you may want to patch test a new product just in case.
Things get a bit more complicated with injections. Polyoxyethylene 60 hydrogenated castor oil acts as a solubilizer, helping oily or stubborn medicines dissolve in water. Regulatory agencies like the FDA make sure manufacturers use only ultra-purified pharma-grade versions for injectables. The main worry with any castor oil derivative in shots comes from allergic reactions. Some drugs for cancer and anesthesia use similar ingredients, and doctors have seen rare but real cases of hypersensitivity or anaphylaxis. Hospitals train staff to recognize and treat allergic responses, but routine use in practice still outweighs these infrequent risks. The general public sees far greater benefit from stabilized drug solutions than the small risk of a reaction—particularly when medical professionals follow dosing and screening guidelines.
Manufacturers source pharmaceutical grades, check every batch for impurities, and keep an eye on patient outcomes. Pharmacopeias and regulatory agencies keep raising the bar for purity, and researchers look out for new data on side effects. I’ve seen medical teams switch to alternative solubilizers if somebody reacts badly, but for the vast majority, polyoxyethylene 60 hydrogenated castor oil handles its job without fuss. Using the right grade, checking for patient allergies, and following tested formulas keep this ingredient in the safe column.
Walk into any lab that uses Polyoxyethylene 60 Hydrogenated Castor Oil, and a few things stand out. This non-ionic surfactant, often called PEG-60 hydrogenated castor oil, has a waxy appearance at room temperature. Slightly off-white, sometimes showing a pearly sheen, it’s solid in the tub but softens up near body temp. Try to scoop it, and it clings—a bit sticky, not brittle. The blend of the hydrogenated castor oil backbone and polyethylene oxide chains creates this unique texture, useful for handling in both industrial and cosmetic work.
Things change up with warmth. Polyoxyethylene 60 Hydrogenated Castor Oil starts melting around 30-40°C. You set it on a warm surface or try to dissolve it in water heated close to bath temperature, and it turns almost transparent, forming a viscous liquid. Temperatures matter not just for solubility, but also for how this compound interacts in an emulsion. Cold rooms, and you’ll find clumping or slow mixing. In practice, heating is not just a technicality, it’s a necessity—especially during production.
In the world of solubility, Polyoxyethylene 60 Hydrogenated Castor Oil bridges gaps. It handles water with ease. Drop a chunk in water, mix, and it dissolves to create a clear to slightly opalescent solution, depending on concentration. This property, driven by its hydrophilic polyethylene oxide groups, puts it high on the list for anyone making clear cosmetics, pharmaceuticals, or food products.
Oils tell a different story. Ask it to blend with pure oils and it resists going solo—but as a surfactant, it pulls stubborn ingredients into the mix, helping form stable dispersions where oil droplets stay suspended. Think of an oil-in-water emulsion for a creamy lotion or a cloudy beverage—this is where PEG-60 hydrogenated castor oil does heavy lifting.
Big companies and craft makers alike turn to Polyoxyethylene 60 Hydrogenated Castor Oil for day-to-day solutions. Water solubility gives it an edge for clear shampoos, facial cleansers, or beverage concentrates, where cloudiness signals trouble. Physical resilience under both heat and moderate mechanical stress makes batch production repeatable. Melt and dissolve cycles don’t degrade it easily. This reliability keeps product recalls low, batch failures rare, and customer confidence high.
Working with surfactants brings challenges, and experience teaches a few things. Without proper temperature control, clumping and poor solubility slow down manufacturing. A small pilot batch can look fine, but scale it up and blending issues sap both time and profit. Investing in precise heating and stirring equipment, as well as good staff training, pays real dividends. In my experience, troubleshooting too-often points back to trying to shortcut the mixing process.
Environmental questions do come up. Derived from castor oil and modified through hydrogenation and ethoxylation, some formulations concern those looking for greener chemistry. Manufacturers now seek methods that minimize air emissions and waste during production or push for higher purity with fewer residual byproducts. This speaks to a broader industry trend—sourcing surfactants that balance function with responsibility. Looking ahead, continuous investment in cleaner technologies and rigorous ingredient transparency builds trust and ensures these workhorse ingredients fit evolving regulatory and market demands.
Every pharmacist and chemist keeps an eye on how ingredients are stored, especially the ones used in making medicines. Polyoxyethylene 60 Hydrogenated Castor Oil, which often lands in syrups, creams, and even as a solubilizer for vitamins, works best when kept under the right conditions. Heat, light, and moisture—these are the real threats in any raw material storeroom. If left unchecked, they spoil or destabilize the product. Patients and professionals trust consistency in medicine, so ingredient reliability can't be an afterthought.
Most sources, including USP and EP guidelines, make it clear: store Polyoxyethylene 60 Hydrogenated Castor Oil in a tightly sealed container. Keep it away from direct sunlight and shield it from high temperatures. A storage temperature of 15°C to 30°C (59°F to 86°F) gives predictable results. Humidity should stay low, and the room needs to be well-ventilated, free from strong-smelling chemicals. Every pharmacist has seen what happens to oils stored near cleaners or paints—contamination and costly waste.
Temperature swings, especially above 40°C, can change the consistency of the oil. It thickens, may separate, or develops an odd smell. It’s surprising how quickly a batch can go from clear to unusable. I’ve watched otherwise careful operators lose entire barrels because of a malfunctioning storeroom thermostat in summer. Routine checks and temperature logs prevent that kind of loss. And yes, a tight-fitting lid isn’t just for keeping out dirt. Polyoxyethylene 60 Hydrogenated Castor Oil absorbs water from the air. Moisture laced with hydrogenated fats is a breeding ground for spoilage.
The standard industry shelf life stretches to 24 months, so two years from production, if the storage instructions get followed. Manufacturers don’t assign this period randomly; they run accelerated stability tests and real-time storage tests. Polyoxyethylene 60 Hydrogenated Castor Oil that sits out too long, or in poor conditions, can fail appearance, odor, or chemical quality tests even before those two years pass. Expiry dates help buyers rotate stock, but the actual shelf life reflects the ingredient’s true resilience against heat, light, and contamination.
If new shipments arrive, workers open one drum at a time. This reduces exposure to humid air and keeps unused product safer for longer. Over the years, I’ve learned that partial drums invite trouble. Seal them at once after use and place them back in the coolest, driest section. Fewer problems show up in quality control if everyone respects this simple routine.
Regulatory standards from BP, EP, and USP give solid guidance, but real quality assurance needs discipline and habits built on experience. Firms that invest in proper storage—air conditioning, temperature monitoring systems, trained staff—see fewer batch fails and customer complaints. Regular audits of storage areas, even as quick spot checks, spot problems before they grow into recalls. Suppliers who keep good records and train their teams cut risk. Patients may never see the storerooms, yet their safety and trust depend on what happens inside those four walls.
Anyone formulating medicines or health products wants to know: will each ingredient really play nice together? Polyoxyethylene 60 hydrogenated castor oil (often called PEG-60 hydrogenated castor oil, or RH 40) pops up all over the place—from oral solutions to eye drops—because it helps dissolve oily substances in water. Yet, not every ingredient shares the same chemistry set. Real chemistry involves more than checking boxes labeled “generally recognized as safe.” Medicines wade into messy territory—different chemical charges, solubility, and competition for space affect how products turn out.
PEG-60 hydrogenated castor oil gets along best with nonionic excipients, meaning those that don’t carry an electric charge. Problems start showing up with certain preservatives—especially parabens. Parabens get used to stop microbial growth in solutions, but combining PEG-60 hydrogenated castor oil has sometimes led to unexpected cloudiness or even visible precipitation in the finished product. Once, while troubleshooting a simple mouthwash recipe, the mixture went hazy within days. Tinkering with concentrations and swapping parabens for benzyl alcohol fixed it. The culprit often amounts to how the surfactant and preservative jostle for position at the droplet’s surface, crowding each other out.
Formulators working with PEG-60 hydrogenated castor oil sometimes run into trouble blending it with certain salts or in hard water conditions. Sodium chloride, calcium, and magnesium salts commonly found in buffered preparations tend to reduce the solubility of PEG-60 hydrogenated castor oil, producing a milky or separated layer. This shows up far more often than you might suppose—even a small jump in electrolyte concentration pushes the excipient past its breaking point. On one project, increasing salt content to speed tablet dissolution resulted in the castor oil dropping out of solution and clumping. Water quality matters way more than most realize. Filtering or softening water helped, but not every facility gets that choice.
Thickeners like polyvinylpyrrolidone sometimes get introduced to boost the stability of suspensions. In practice, adding PEG-60 hydrogenated castor oil with certain grades of PVP or crosslinked polymers can trigger unexpected gelation or, at the very least, unwanted thickness. The two excipients interact, leaving the final product far too viscous for dosing. One solution switched out the thickener for a cellulose-based option—avoiding the “gummy” aftermath. This outcome doesn’t always get picked up in small-scale tests, so scale-up or temperature variation can bring surprises.
Patients ultimately feel these incompatibilities, whether it’s a gritty drop, cloudiness that looks unsafe, or even changes in taste. Undissolved ingredients don’t just affect looks—they can impact dosing accuracy or shelf life. Recent regulatory recalls over visible crystallization in eye drops drew public attention. Keeping a watchful eye for these interactions goes beyond compliance; it builds medical trust. It’s tempting to assume every listed excipient will blend effortlessly, but that’s not reality in formulation labs.
Experienced formulators test every combination at multiple concentrations and temperatures. Running accelerated stability studies under different lighting and storage conditions gives insight that benchtop studies miss. Choosing alternative surfactants, screening excipients together from the outset, and working closely with ingredient suppliers can all make a difference. Reading up on documented cases and consulting regulatory databases like the FDA’s Inactive Ingredient Database ensures fewer surprises down the line—keeping medicines safe, stable, and effective for the people who rely on them most.
| Names | |
| Preferred IUPAC name | Polyoxyethylene (60) hydrogenated castor oil |
| Other names |
PEG-60 Hydrogenated Castor Oil Polyoxyl 60 Hydrogenated Castor Oil Cremophor RH 60 Solutol H60 Hydrogenated Polyoxyethylene Castor Oil Polyethoxylated Hydrogenated Castor Oil Polyoxyethylenated Hydrogenated Castor Oil |
| Pronunciation | /ˌpɒliˌɒks.iˌɪˈθiːl.iːn sɪkˈstiː haɪˌdrɒdʒ.ə.neɪ.tɪd ˈkæs.tər ɔɪl/ |
| Identifiers | |
| CAS Number | 61788-85-0 |
| Beilstein Reference | 1811065 |
| ChEBI | CHEBI:131107 |
| ChEMBL | CHEMBL1201568 |
| ChemSpider | 58842832 |
| DrugBank | DB11097 |
| ECHA InfoCard | 03e7e1d9-c138-4ac2-8d31-5204cda4bf82 |
| EC Number | 61791-12-6 |
| Gmelin Reference | 1253583 |
| KEGG | C16155 |
| MeSH | D018382 |
| PubChem CID | 5284449 |
| RTECS number | WLN7066020 |
| UNII | 0GH35QWA43 |
| UN number | UN3082 |
| CompTox Dashboard (EPA) | DTXSID30889673 |
| Properties | |
| Chemical formula | C₆₂H₁₂₂O₆₀ |
| Molar mass | 1000–1300 g/mol |
| Appearance | Appearance: "Yellowish oily liquid |
| Odor | Odorless |
| Density | 1.05 g/cm³ |
| Solubility in water | Soluble in water |
| log P | 2.81 |
| Vapor pressure | Negligible |
| Basicity (pKb) | 7 |
| Refractive index (nD) | 1.453 – 1.457 |
| Viscosity | Viscosity: 60–160 poise |
| Dipole moment | 2.62 D |
| Pharmacology | |
| ATC code | A06AG11 |
| Hazards | |
| Main hazards | May cause eye and skin irritation. May cause respiratory tract irritation. |
| GHS labelling | GHS labelling: Not classified as hazardous according to GHS (Globally Harmonized System). No pictogram, signal word, hazard statement, or precautionary statement required. |
| Pictograms | GHS07, GHS09 |
| Hazard statements | No hazard statement. |
| Precautionary statements | Keep container tightly closed. Store in a cool, dry, and well-ventilated place. Avoid contact with eyes, skin, and clothing. Wash thoroughly after handling. In case of contact, rinse immediately with plenty of water and seek medical advice. |
| NFPA 704 (fire diamond) | 1-1-0 |
| Flash point | > 250°C |
| Autoignition temperature | > > > 370°C |
| Lethal dose or concentration | LD50 (oral, rat): > 5,000 mg/kg |
| LD50 (median dose) | > 7.5 g/kg (rat, oral) |
| NIOSH | TRN59545 |
| PEL (Permissible) | PEL not established. |
| REL (Recommended) | 10 mg/m³ |
| IDLH (Immediate danger) | Not established |
| Related compounds | |
| Related compounds |
Polyoxyethylene Hydrogenated Castor Oil PEG-60 Hydrogenated Castor Oil Cremophor RH 60 Polyoxyethylene Castor Oil Polyoxyl 60 Hydrogenated Castor Oil Hydrogenated Castor Oil Ethoxylate Ethoxylated Hydrogenated Castor Oil |
Chengguan District, Lanzhou, Gansu, China
