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4-Clorobutilveratrato BP EP USP Pharma Grade stands as a pharmaceutical raw material with a reputation for stability and consistent performance across a range of chemical processes. This compound, relied on by laboratories and pharmaceutical manufacturers, carries a molecular structure that features a chlorine-substituted butyl group connected to the veratrate backbone. Chemists recognize this compound by its molecular formula C13H17ClO4, and a molecular weight around 272.72 g/mol. This structure, with its aromatic rings and ether linkages, shapes its physical and chemical profile in meaningful ways, influencing reactivity, solubility, and handling protocols.
In practice, 4-Clorobutilveratrato typically appears as a flaky solid, though certain production batches yield it as fine powder or compact crystals, all displaying a slightly yellowish or off-white hue. The tactile sense tells a story here—samples range from grainy to slippery, reflecting how molecular arrangement drives every physical nuance. Packing density matters on the warehouse shelf, and with this compound that value commonly settles near 1.22 g/cm³ at 20°C. It’s not unusual to encounter shipments labeled as pearls or flakes; both forms result from specific manufacturing approaches but offer equivalent reactivity. Chemists charged with compounding solutions measure its solubility in standard solvents, finding limited mobility in water but ready dissolution in organic carriers, which fits the profile of many pharmaceutical intermediates.
The molecule’s backbone includes a 4-chlorobutyl chain attached through an ester linkage to a veratric acid core. Each atom’s placement—each bond angle—matters, with the chlorine substituent adding both weight and a unique reactivity pattern. This affects not only how it interacts in larger synthesis schemes but also how handlers treat spills, monitor for accidental releases, and gauge resistance to breakdown under heat or ultraviolet light. Reagents that target esters or alkyl halides interact strongly, with breakdown products sometimes posing their own safety points to address.
Materials qualifying for BP (British Pharmacopoeia), EP (European Pharmacopoeia), or USP (United States Pharmacopeia) grading face an intense battery of analytical checks. Users can reasonably expect purity levels above 98%, with strict attention paid to heavy metal content, organic residue limits, and moisture. Analytical chemists confirm identity by infrared spectroscopy, nuclear magnetic resonance, and high-performance liquid chromatography. Spectra show signature bond vibrations, giving lab technicians tools for batch release and troubleshooting. Labs receiving the raw material check density, melting point, and refractive index—a practical routine that flags deviations early and keeps quality issues out of the end user’s hands.
Governments track international shipments using the Harmonized System (HS) code; for this compound, shippers usually classify it under 2915.90, which covers other aromatic acids and derivatives. This code speeds cross-border paperwork but also sets customs officers on the lookout for restricted or controlled substances. Occupying a midpoint on the spectrum of chemical safety, workers recognize 4-Clorobutilveratrato as potentially harmful in concentrated form, prompting most facilities to require gloves, eyewear, and careful ventilation for large-scale handling. Safety data sheets flag it as hazardous on ingestion, inhalation, or significant skin exposure. The chlorine atom increases toxicity relative to its parent compound. If fire strikes a warehouse storeroom, responders plan for corrosive and possibly toxic gases, reinforcing that controlled storage matters. Emergency kits with spirulina-based absorbents or neutralizing agents keep accidental release from escalating into larger incidents.
4-Clorobutilveratrato plays a behind-the-scenes role as a building block or intermediate, helping chemists piece together more complex active ingredients. Pharmaceutical research values compounds with predictable structure and behavior, so having tightly specified raw material batches consistently reduces manufacturing headaches. Producers typically source kilo-scale lots or liters of pre-mixed solutions, each packed by weight or volume according to downstream demand. This fits into a larger ecosystem of regulated suppliers and buyers who trade not only on cost but on reliability, documentation, and transparency of raw materials.
Managing waste streams generated during use draws as much attention as the original manufacturing process. Chlorinated organics often show up in wastewater, prompting producers to implement carbon filtration, advanced oxidation, or bio-remediation steps before discharge. Pharmaceutical companies devote increasing resources to satisfying evolving guidelines from REACH, EPA, and local regulators, pushing for lower environmental residue and improved worker safety. Documentation trails—from incoming goods receipts to batch records and disposal manifests—show investigators every handoff, upholding traceability and accountability.
Addressing concerns about hazardous properties and environmental impacts calls for better ways to capture, treat, and recycle waste streams, as well as improving in-plant controls over air handling and worker exposure. Some organizations invest in green chemistry alternatives, tweaking synthetic pathways to reduce or eliminate the need for chlorinated intermediates. Others advocate for more detailed transparency between suppliers and manufacturers, with blockchain technology and digital batch records creating a tight chain of custody for every drum of raw material. Training for warehouse and laboratory staff—practical, scenario-based programs—builds competence and confidence, promoting tighter safety culture. Collaboration among chemical suppliers, pharmaceutical manufacturers, regulators, and public health officials forges solutions that fit both technological and budget realities.
Chengguan District, Lanzhou, Gansu, China
