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Dl-A-Tocopherol, often considered the fully synthetic form of Vitamin E, brings significant applications to various industries, from pharmaceuticals to cosmetics and food fortification. Pharma grade material means the compound meets stringent quality standards set by respected pharmacopeias—BP (British Pharmacopoeia), EP (European Pharmacopoeia) and USP (United States Pharmacopeia). Vitamin E, including its different variations, has always fascinated with its reputation for antioxidant features. This variant goes through precise purification and advanced processes to ensure quality at every level—there is no room for guesswork in demanding industries where health and safety come first.
Dl-A-Tocopherol carries the molecular formula C29H50O2. Structurally, it represents a blend of eight isomers with the core chromanol ring and a phytyl side chain. Chemists can easily spot its density around 0.950 to 0.970 g/mL at 20°C. The clear, viscous, slightly yellowish liquid tells you immediately that you’re not dealing with a simple sugar or salt. This is a fat-soluble vitamin, so water just rolls right off it. From a molecular point of view, that means it disperses perfectly in oils and lipid-based formulations. Its refractive index sits sharply between 1.494 and 1.498 at 20°C, a handy figure for anybody working to identify purity and concentration.
You rarely come across Dl-A-Tocopherol in powder or solid forms at room temperature. This pharma grade compound generally appears as a heavy liquid, golden to pale amber, with a mild, characteristic odor. Yet, with the right processes, it can be made into crystals or even into flakes, though that route sees more lab-scale action than commercial deployment. Some specialty applications push for pearls or beadlets, mostly to help with measuring or blending in solid matrices. Truth is, most industrial and pharma users stick with the liquid, which carries a viscosity between 400 and 800 mPa·s at 20°C. This ease of use makes accurate dosing practical in manufacturing lines, whether you’re working with liter volumes or micro-batches for labs.
Spec sheets for Dl-A-Tocopherol BP EP USP Pharma Grade demand high assay—98% or greater is the norm. The USP reference standard demands a minimum content based on sophisticated chromatographic analysis. It carries strict controls on heavy metals, acid value (max 1.0), and specific rotation (between +24° and +29° using a 2% solution in absolute alcohol). These controls do not just protect public health—they also guarantee functionality in processes ranging from tablet pressing to liquid softgel production. Checking batch certificates often reminds you how regulatory frameworks bring dependable safety to global supply chains.
The HS Code for Dl-A-Tocopherol hovers around 2936.28, designated for vitamins and derivatives. This code simplifies shipping, customs declarations, and regulatory reporting. The international trade of vitamin compounds reaches into billions, where reliable labelling and traceability provide the transparency that global partners depend on.
Dl-A-Tocopherol does not qualify as a hazardous chemical by most international transport regulations, making it easier for labs and manufacturers to store and ship. Still, guidelines call for gloves and goggles when handling large quantities, since the pure form could cause mild skin or eye irritation. Vitamin E as an ingredient breaks down in the open air and in light, so airtight, dark-glass packaging keeps it potent until it’s blended or dosed into final products. From my own experience, open containers left on a bench over a weekend can lead to measurable losses, so tight SOPs really matter. Waste disposal should meet local chemical waste protocols. Any spills clean up easily with absorbent material and soap, but letting unreacted compound reach water supplies is best avoided, even though toxicology profiles point to low overall risk.
Dl-A-Tocopherol lays the foundation for many finished health goods. Its antioxidant power preserves active ingredients in creams, serums, tableted multi-vitamins, and specialized animal feeds. It prevents the rancidity of oils, keeping them fresh for longer. Hydration and emulsion stability in topical formulas owe much to this vitamin. In the pharmaceutical world, stability means the difference between a working solution and one that breaks down before it ever hits a patient’s hands. For builders of prescription and over-the-counter medicines, compliant sourcing and validated analytical data steer clear of regulatory headaches down the line. This is why partnerships among labs, suppliers, and inspectors focus on complete transparency about material origins and lot-by-lot testing.
High-quality Dl-A-Tocopherol BP EP USP Pharma Grade shows us how vital raw material stability is for reliable product outcomes. In drug formulation, cheap or unstable input affects potency, shelf life, and can compromise patient safety. Years spent in laboratory environments working on dietary supplements and wound care ointments gave me direct evidence of the challenges that come with poor raw material control—one faulty batch can mean costly recalls or regulatory fines. Most process chemists and formulators develop close relationships with their vitamin E suppliers for this reason, relying on phone calls, transparency, and sharing results to tackle new issues like micro-contaminants or shifting international specs.
Few chemicals have bridged the gap between lab, health, and everyday life as smoothly as Dl-A-Tocopherol. Its reach highlights the need for accurate labelling, consistent quality, and environmental responsibility from all players in the value chain. Improving tracking, investing in green chemistry, and updating workers on safety guidelines will drive better results for industries and consumers alike. Responsible stewardship depends on combining evidence-based protocols, user education, and ongoing dialogue between producers and regulators. This keeps Dl-A-Tocopherol ready for whatever demands tomorrow’s markets bring.
Chengguan District, Lanzhou, Gansu, China
