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Hydroxyquinoline Sulfate BP EP USP Pharma Grade stands out as an essential compound in pharmaceutical manufacturing and laboratory settings. This chemical raw material plays a central role for those who formulate antimicrobial agents, antiseptics, and complex drug preparations. Manufacturers often turn to it because of its stringent compliance with official pharmacopoeial guidelines including British Pharmacopoeia (BP), European Pharmacopoeia (EP), and United States Pharmacopeia (USP). These regulatory markers set the quality and purity bar high, meaning that much of the pharmaceutical world places a premium on using sources that match these criteria. Hydroxyquinoline Sulfate comes from the hydroxyquinolines family, chemicals recognized for their chelating abilities and contribution to therapeutics, especially as broad-spectrum antiseptics.
In terms of appearance, the sulfate form generally presents as a crystalline solid, white to off-white in color. Sometimes it arrives in powder or flake form, depending on the processing stage and storage method. Its density registers close to 1.7 g/cm³. Reactivity tends to stay low under ambient conditions, but like many pharmaceutical-grade chemicals, the material demands careful handling. Solubility sets it apart — this compound dissolves readily in water and alcohol, giving pharma scientists options during synthesis and formulation. As a solution, Hydroxyquinoline Sulfate holds stability across a range of temperatures and storage scenarios, especially when shielded from light and moisture. The product stays in solid form for warehouse transport and moves into crystalline or powder states for actual medication production. Whether delivered by the kilogram, ton, drum, or smaller laboratory vial, the form factor always impacts safety, dissolution rate, and ease of use.
The molecular formula for Hydroxyquinoline Sulfate lands at C9H7NO·H2SO4. Studying its structure, the core contains a hydroxyquinoline base, which brings high binding affinity for metals and targets within biological systems. This affinity explains why healthcare settings frequently use it to limit microbial growth on skin, wounds, and medicinal equipment. The sulfate counterion supports compound stability, reducing volatility and making bulk storage less hazardous compared to some other forms. Chemical property data draws a clear boundary: it melts between 201 and 202°C. Its water solubility and sulfate composition both drive its strong performance as an intermediate for various finished products.
Pharma-grade Hydroxyquinoline Sulfate follows a strict set of quality checks. Purity hovers at 98% or higher, ensuring therapeutic-grade performance. Impurity limits, especially for heavy metals like lead, arsenic, and cadmium, meet ultra-low thresholds, often in the single-digit parts-per-million range. Every batch passes through identification tests (using infrared absorption and HPLC), loss on drying (max 1%), and sulfated ash analysis. These checks follow BP, EP, and USP compendia methodologies. Material consistency remains the center of every release — unchecked impurity rises or density changes quickly disqualify an entire production lot. End-users working with antibiotics, antiseptics, or certain anti-microbial agents often demand certificates that verify these test results. In day-to-day reality, labs count on such tight specifications: poorly controlled lots can endanger drug sterility and patient safety.
For international trade, Hydroxyquinoline Sulfate carries the Harmonized System (HS) code 2933.39.00. This category fits organic compounds, specifically heterocyclic chemicals with nitrogen. Regulatory agencies, customs authorities, and global buyers use the HS code to identify shipments, streamline import and export, and determine tariffs. By referencing the code, suppliers and manufacturers side-step confusion in global markets and trace shipments back to specific raw materials needed for compliance audits. The correct HS code remains crucial not just for customs clearances but also for making sure pharmaceuticals importation laws align across countries. Mistakes in coding can stall raw material delivery, leading to delays in downstream drug production lines.
Hydroxyquinoline Sulfate arrives in a few arrangeable physical forms based on application: solid blocks or crystals for storage, powder for synthesis, flakes for dissolution, sometimes even pearls for controlled release. Each form matters in pharmaceutical development. Powders dissolve rapidly in solvents for quick batch production. Crystals help those looking for extended shelf life and minimal surface contamination. Some industry veterans appreciate the traditional pearl form, which limits airborne dispersal and wastage in open-batch environments. Liquid solutions, although less common, find use in diagnostics where immediate application or further dilution is a must. Bulk material handling typically sticks to solid or flake forms, packed tightly in FDA-compliant double-lined drums to shield against moisture and environmental damage.
Those who’ve worked with raw chemical stock know: hydroxyquinoline compounds never count as casual-use materials. Hydroxyquinoline Sulfate stays relatively stable, yet exposure can still irritate skin, eyes, and mucous membranes. Inhalation of dust or powder raises similar red flags — always wear gloves, goggles, and an industrial-grade mask. Safety data sheets point to possible mutagenic or reproductive risks, which means responsible labs routinely isolate handling and storage away from other raw materials. The material calls for designated spill procedures and neutralization agents in case of accidental release; all waste disposal flows through chemical incineration or properly licensed hazardous waste handlers. Despite these hazards, the pharmaceutical industry relies on its performance, offsetting risk with a strict PPE culture and detailed training programs.
Longtime industry professionals recognize Hydroxyquinoline Sulfate’s role stretches far beyond antiseptics. It feeds into dye manufacture, metal ion detection, and biochemistry research. In pharma, it underpins topical creams, wound powders, oral solutions, and certain investigational compounds. Chemists appreciate its utility: the molecular core binds tightly with bacterial cell walls, delivering broad-spectrum antimicrobial action that stops pathogens from growing or spreading in vulnerable patients. With global demand for sterile drug production on the rise, dependable supply chains for this raw material shape both local pharmacies and international finished product markets. Skipping on quality, or subbing this sulfate for off-grade stocks, would cut the legs out from any formulation claiming high healing potential.
Tighter regulatory oversight helps prevent safety lapses. Transparent procurement—meaning every manufacturing lot comes with a batch-specific certificate of analysis—defends against contamination scares. Implementing digital inventory tracing systems lets downstream users verify every drum’s origin and journey. For facilities handling large batches, investing in local air filtration and spill containment infrastructure reduces on-site accident risks. On the compliance front, training programs built around hazard communication standards connect lab and warehouse teams, making sure everyone recognizes warning labels and proper disposal procedures. Waste streaming, with dedicated chemical-neutralization protocols, cuts down on environmental contamination and legal exposure. For those designing new formulations, pilot-scale runs with this sulfate, monitored via real-time analytics, tease out handling quirks and unexpected reactivity, minimizing surprise setbacks. Solid supply partnerships, built on clarity over raw material properties, pay off long term—nobody wants their process held up by a questionable lot or missing documentation.
Chengguan District, Lanzhou, Gansu, China
