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Mogroside BP EP USP Pharma Grade comes from Luo Han Guo, sometimes called monk fruit, and serves as a sweetener and pharmaceutical ingredient. Its molecular structure features glycoside compounds, making it strikingly sweet without providing calories. Mogroside holds a molecular formula of C60H102O29 and a molecular weight of around 1287.41 g/mol. As a purified extract sourced through rigorous methods, this compound meets the standards laid out by pharmaceutical guidelines such as the British Pharmacopoeia (BP), European Pharmacopoeia (EP), and United States Pharmacopeia (USP). These standards confirm not just its purity but ensure repeatability and reliability for medical, food, and industrial uses. For classification and shipping, its HS Code is generally 2938909090, which falls under glycosides and their derivatives.
Mogroside BP EP USP Pharma Grade appears in several physical states, typically as a fine white to off-white crystalline powder, though denser flakes and pearls can also be found. This diversity comes from differences in purification and drying. The powder form feels light and disperses quickly, while the flakes offer a more compact feel. Sometimes material comes as a solid crystalline chunk, though this is rarer in pharma applications. Mogroside melts around 197–207°C and dissolves easily in water, making it a practical choice for liquid solutions and pharmaceutical preparations. Density stands at roughly 1.6 g/cm3. Water solubility means you can mix it into solutions up to 10% by mass under ambient conditions without trouble.
As a glycoside, mogroside contains both sugar and non-sugar molecules, which carry intense sweetness—up to 250 times that of sucrose—for applications needing sugar substitutes without the blood glucose spike. The structure holds steady under normal storage but starts to degrade after prolonged exposure to strong acids and oxidizing agents. In the solid, Mogroside handles temperatures for routine processing without much breakdown. None of the usual components act as strong oxidizers or reducers. While not volatile or flammable under room temperature, dust clouds can form in unventilated storage.
Manufacturers of BP EP USP Pharma Grade Mogroside guarantee a purity range often above 80%, measured by high-performance liquid chromatography (HPLC). Water content sits below 5%, helping prevent caking or degradation. Most materials test negative for residual solvents and heavy metals according to pharmaceutical norms, and microbiological counts (TAMC, TYMC) stay well below specification limits. Additives, preservatives, or flowing agents do not typically appear in pharma-grade mogroside, so it fits for strict applications like tablets, syrups, or even injectable solutions. Granule size can fall anywhere from 20 to 80 mesh, so the user can select finer powders for rapid dissolution or opt for coarser flakes to ease handling during manufacturing.
Consuming mogroside in quantities found in food and pharma products shows little to no toxicity in available studies, making it a preferred option for people sensitive or allergic to artificial sweeteners. Still, bulk mogroside powder may irritate sensitive skin, eyes, or respiratory tracts, especially during processing. Material Safety Data Sheets (MSDS) recommend gloves, masks, and proper ventilation. The compound does not show cumulative or chronic toxicity in animal models, and regulatory agencies, including the US FDA and EFSA, have flagged it as safe within customary limits. Mogroside itself does not qualify as hazardous or harmful under chemical law, with no environmental persistence or bioaccumulation. Storage calls for cool, dry settings, away from strong acids, bases, and oxidizing agents.
Raw mogroside extraction starts with dried monk fruit, which grows mainly in Guangxi province, China. The fruits undergo hot water extraction, then various chromatographic steps separate individual mogrosides, such as Mogroside V, to meet BP, EP, and USP standards. Reputable suppliers document full traceability back to non-GMO plant sources, without the use of ethical or biological contaminants. Labs and manufacturers demand compliance documentation, including Certificates of Analysis (COA) and trace batch numbers, before material clearance for pharmaceutical manufacturing.
Formulators in the pharmaceutical industry use mogroside as a low-calorie sweetener for cough syrups, chewable tablets, lozenges, and other products where taste-masking and caloric reduction play key roles. Food makers lean into mogroside to lower sugar content in drinks, sauces, baked goods, and confectionery, supporting consumer health goals and regulatory sugar mandates. The consistent molecular profile delivered by pharma-grade mogroside makes formulation more reliable, which supports effective dosing and taste control. Due to biomolecule origin and clean extraction, it works for vegan, kosher, and halal production lines. In research and development, high-purity mogroside opens paths for new therapies and nutraceuticals, especially in metabolic, digestive, and sugar-replacement studies.
People working with mogroside need to balance sustainability, reliability, and fair labor in their supply chain, given that primary raw material harvest takes place in specific rural pockets. Weather and environmental policy in Guangxi province affect year-to-year harvests, creating bottleneck risks for global supply. Global regulation of natural sweeteners remains patchy, especially concerning label claims, maximum dosage, and additive status. Some countries still view mogroside as a food additive, not a recognized sweetener, which means expert legal and regulatory review matters for market expansion. Cost of high-grade, pharma-pure mogroside exceeds that of low-volume food-grade or unspecified extracts, reflecting higher QA/QC requirements.
A robust supply network between monk fruit growers, extraction facilities, and end-users helps even out seasonal fluctuation and price spikes. Oversight from international bodies and cooperation between national regulatory agencies encourage standard rule-setting for labeling, purity, and permitted uses. Investment in new purification and drying technologies lowers energy needs, increases extraction yield, and limits by-product waste, keeping costs manageable. Education of end-users in pharma and food production matters, as the use of high-purity compounds requires both technical awareness and regulatory compliance to meet rising health and safety standards. By working with local farming co-ops and promoting sustainable harvesting methods, manufacturers can help keep raw materials flowing and ensure fair compensation for labor.
Chengguan District, Lanzhou, Gansu, China
